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A clinical trial to study the effect of spinal morphine in reducing the requirement of locally anesthetizing drugs in labour analgesia

Analgesic efficacy and Local anaesthetic sparing effect of intrathecal morphine as adjuvant to labor analgesia - A Double blinded prospective randomised controlled trial - RCT

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024119
Enrollment
70
Registered
2020-03-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Group M -Intrathecal morphine: Drug - Intrathecal morphine 250 mcgs + Bupivaciane 2 mg + Fentanyl 25 mcgs at the onset of labour pain followed by epidural catheterisation and epidiral a

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I and II 2.Primi gravida/ Mutigravida, para 0 3.Uncomplicated singleton pregnancy 4.Vertex presentation 5.Active labour 6.Requesting for labour analgesia

Exclusion criteria

Exclusion criteria: - Local or systemic infection - Patient not willing to participate - Known allergy to study drugs - Bleeding disorders - Decreased platelet counts - Usage of opioids/other analgesics in last 4hours

Design outcomes

Primary

MeasureTime frame
Effect of intrathecal morphine on Local anaesthetic requirement epidurally during labourTimepoint: Every 30 minutes till delivery, then every 6 hours postnatal till 24 hours.—

Secondary

MeasureTime frame
Effect of intrathecal morphine on 1. Pain scores by VAS in I, II and III stages of labour 2.Incidence of maternal nausea and vomiting , urinary retention and pruritus 3.Rate of instrumental delivery 4.APGAR scores at 1 , 2 and 5 minutes 5. Maternal satisfaction (assessed by a subjective scale) Timepoint: Every 30 minutes till delivery and then postnatal every 6 hours for 24 hours.—

Countries

India

Contacts

Public ContactRushil Vladimir R

AIIMS , New Delhi

drsrajeshwari@gmail.com09868397810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026