Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: Intralesional platlet rich plasma and intralesional methotrexate in one group
Intralesional methotrexate alone in one group: 66 Patients will be randomly divided into three groups as
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: Patients of more than 18 years of age attending the Dermatology OPD during the study period with stable plaque psoriasis for 6 months, involving 10%of body surface area and minimal PASI of 10 at screening will be included. Patient who has not undergone any prior systemic or topical treatment. Those who are giving consent to participate in the study. Those who are willing for follow up.
Exclusion criteria
Exclusion criteria: Patients who received any other treatments for their psoriasis before enrolment,renal,liver impairment, pregnancy, fever,infection, pustular psoriasis & immunosuppressed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify the clinical efficacy of treatment for chronic plaque psoriasisTimepoint: 4-6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify the better treatment regimen for chronic plaque psoriasis. To identify the side effects and recurrence rate following treatmentTimepoint: 4-6 months | — |
Countries
India
Contacts
Public ContactYuva priya
Madras medical college
Outcome results
None listed