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Dexamethasone and Magnesium Sulphate gargle for prevention of sore throat after general anaesthesia

Effect of Dexamethasone gargle and MgSO4 gargle on incidence and severity of post operative sore throat in patients undergoing surgery under general anaesthesia : A randomised comparative study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/024064
Enrollment
60
Registered
2020-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: PCS-

Interventions

Intervention1: Gargles: Gargle with 8mg Dexamethasone in 20 ml of 5% dextrose . Control Intervention1: Gargle: Gargle with 1gm MgSO4 in 20 ml of 5% dextrose

Sponsors

Rohilkhand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient posted under General Anaesthesia with duration American Society of Anestehsiologist (ASA) grade I or II Between age 18-50 years of either sex

Exclusion criteria

Exclusion criteria: Patient refusal for procedure. History of recent respiratory tract infection. History of pre-operative sore throat. Smoking habit. Patient on long term steroid or analgesic treatment. Patient on chronic treatment with Magnesium.

Design outcomes

Primary

MeasureTime frame
Incidence of post operative sore throat .Timepoint: 24 hours after surgery—

Secondary

MeasureTime frame
Incidence of sore throat . Severity of sore throat . Incidence of cough and hoarseness of voice .Timepoint: 0,2,4,6 and 24 hours after surgery . 0,2,4,6 and 24 hours after surgery . Within 24 hours of surgery.—

Countries

India

Contacts

Public ContactTamanna Baktier

Rohilkhand Medical College

docneehars@gmail.com7037128239

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026