Health Condition 1: K269- Duodenal ulcer, unspecified as acute or chronic, without hemorrhage or perforation Health Condition 2: K30- Functional dyspepsia Health Condition 3: K259- Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation Health Condition 4: K299- Gastroduodenitis, unspecified Health Condition 5: K279- Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation
Conditions
Interventions
Intervention1: Triple Drug Regimen PAC: Tab Pantoperazole 40 mg BD half hour before meals per oral x 14 days,
Cap Amoxicillin 1gm (500mg, 2 capsules) BD per oral X 14 Days,
Tab Clarithromycin 500mg BD
Sponsors
DR Rajendra Prasad Government Medical College Kangra at Tanda
Eligibility
Inclusion criteria
Inclusion criteria: Dyspepsia patients (ulcer or non-ulcer) with H. pylori positivity on gastric biopsy.
Exclusion criteria
Exclusion criteria: 1) Patients not willing to give written informed consent. 2) Pregnant females. 3) Lactating females. 4) Active alcohol users. 5) Patients allergic or with known contraindications to any of study drugs. 6) Patients who have already taken either of the above mentioned H. pylori eradication regimens.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication of Helicobacter pylori as indicated by stool antigenTimepoint: 1.5 months after initiation of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the safety profile of two triple drug regimenTimepoint: From initiation of treatment to 1.5 months after initiation of treatment. | — |
Countries
India
Contacts
Public ContactDr Dinesh Kansal
DR. Rajendra Prasad Government Medical College Kangra at Tanda
Outcome results
None listed