Health Condition 1: G958- Other specified diseases of spinalcord
Conditions
Interventions
Intervention1: Vidil-3 plus bolus dose of vitamin D (Cholecalciferol): Conventional as in Group 1 and in addition, 600000 IU of vitamin D3 orally in 10 divided doses (60000 IU continuously for ten day
Sponsors
Dr R N Srivastava
Dr Wahid Ali
Prof Raja Roy
Eligibility
Inclusion criteria
Inclusion criteria: 2. ASCI less than 6 weeks of injury 3. Motor complete thoracolumbar injury (AIS A, B), 4. TLISS greater than or equal to 4 requiring surgical stabilization 5. Hypovitaminosis D: 25(OH) D levels less than 30ng/ml
Exclusion criteria
Exclusion criteria: 1. Other associated injuries such as major thoracoabdominal injuries & head injuries needing intervention. 2. Neuro-psychiatric patients and patients on steroid or other immunosuppressant therapy or other comorbid conditions making subjects unfit for surgery 3. Subjects who do not give consent for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Assessment- Neurological status- at baseline, at 3rd week 3rd and 6 months Nutrition status- at baseline at 3rd week 3rd and 6 monthsTimepoint: At baseline at 3rd week 3rd and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life (QoL) Assessment: Spinal Cord Independence Measure (SCIM) questionnaire will be used; At baseline, 3rd week, 3rd and 6 months. Metabolites status: Glycine and succinate profiling of serum bio-fluid in acute spinal cord injury in order to elucidate their possible role as prognostic indicator of neurological recovery.Timepoint: At baseline, at 3rd week, 3rd and 6 months. | — |
Countries
India
Contacts
Public ContactAlka Singh
Dept. of Orthopaedic Surgery King Georgeâ??s Medical University
Outcome results
None listed