Health Condition 1: O80- Encounter for full-term uncomplicated delivery Health Condition 2: O80- Encounter for full-term uncomplicated delivery
Conditions
Interventions
Intervention1: Phenylephrine: Intravenous infusion will be started at rate of 100 µg/min, just at start of intrathecal injection, till the delivery of the baby.
Control Intervention1: Noradrenaline: I
Sponsors
Apoorva Singh
Eligibility
Inclusion criteria
Inclusion criteria: Full term, non-labouring pregnant females ASA physical status II Scheduled for elective CD under spinal anaesthesia
Exclusion criteria
Exclusion criteria: Refusal of the patient to participate in the study. Any known co-morbidities, such as hypertensive disorders of pregnancy, diabetes, cardiovascular diseases, cerebrovascular diseases, established presence of arrhythmias. Any known fetal abnormality or fetal distress, multiple gestation, ruptured membranes with meconium stained liquor, growth restricted foetus having chronic asphyxia (previous abnormal non-stress test and biophysical profile Recent use of any vasoactive medication. Any contraindication to spinal anaesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cord blood base deficit in noradrenaline group as compared to phenylephrine groupTimepoint: At the time of delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| APGAR scores of the neonateTimepoint: 1 minute, 5 minutes and 10 minutes;Final outcome of the neonate and neonatal mortalityTimepoint: At the time of discharge from hospital;Intraoperative nausea, vomiting, headacheTimepoint: Intraoperatively;Maternal hemodynamicsTimepoint: Intraoperatively;Requirement of neonatal resuscitationTimepoint: After birth;Umbilical artery blood PaCO2Timepoint: At the time of delivery;Umbilical artery blood PaO2Timepoint: At the time of delivery;Umbilical artery blood pHTimepoint: At the time of delivery | — |
Countries
India
Contacts
Public ContactApoorva Singh
Post Graduate Institute of Medical Education and Research
Outcome results
None listed