Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Group A :Intrathecal 0.5% bupivacaine heavy 3.4 ml plus 5 µg dexmedetomidine
Group B& C : Intrathecal 0.5% bupivacaine heavy 3.4 ml and Intra venous dexmedetomidine 0.5 µg/Kg bo
Patients in group B will be given intrathecal 0.5% bupivacaine heavy 3.4 ml (17mg) and IV dexmedetomidine 0.5 µg/Kg body weight in 50 ml of normal saline as an IV infusion over 10 minutes, 20 minute
Sponsors
Gayatri vidya parishad Institute of health care and medical technology
Eligibility
Inclusion criteria
Inclusion criteria: Study population will consist of Eighty adult patients of age between 18 and 70 years, body weight between 40and 70 Kg, height between 145 and 170 cm and who are of American Society of Anaesthesiologists (ASA) physical status grade I and II of either sex and attending our Medical College Hospital for elective lower limb and lower abdominal surgeries lasting less than 2 hours in duration between the period from 15-3- 2020 to 31-8 -2020 and who do not have our exclusion criteria.
Exclusion criteria
Exclusion criteria: Exclusion criteria adapted for our study include patients with known allergy to study drugs, patient refusal of local anaesthetic block, patients suffering from neurological disorders, psychiatric disorders, mental retardation, uncontrolled hypertension and diabetes mellitus, patients having coagulation or bleeding abnormalities, severe spinal deformity, patients on Calcium channel blockers/angiotensin-converting-enzyme (ACE) inhibitors/clonidine/β-blockers, sedative medications/opioids/antidepressants in the week prior to surgery, infection at spinal injection site or any contraindication to spinal anesthesia. and cases of caesarean section.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variables studied will be the differences in the duration of the sensory and motor blocks.Timepoint: Duration of sensory block will be assessed when the patient complains of pain after recovery from the spinal block Duration of motor block will be assessed when the patient recovers complete motor function after the spinal block | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome variables studied will be differences in the onset of block both motor and sensory, haemodynamic variables heart rate (HR), mean arterial pressure (MAP),systolic blood pressure (SBP) diastolic blood pressure( DBP), respiratory rate (RR) and Peripheral arterial oxygen saturation (SaO2),Timepoint: every 5 min for the initial 30 min and later at every 15 min till the end of surgery and at every 30 minutes till the recovery of sensory and motor block. | — |
Countries
India
Contacts
Public ContactRamana Reddy MV
Gayatri Vidya Parishad Institute of Health Care and Medical Technology
Outcome results
None listed