Health Condition 1: L270- Generalized skin eruption due to drugs and medicaments taken internally
Conditions
Interventions
None listed
Sponsors
PGIMER chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA FOR CASES: 1. Patients diagnosed as possible, probable and definitive DRESS syndrome (according to RegiSCAR criterion) 2. Age > 12 years. INCLUSION CRITERIA FOR CONTROLS: 1. Patients having drug induced maculopapular drug reaction and diagnosed as â??No DRESSâ?? according to RegiSCAR criterion. 2. Age > 12 years
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA FOR CASES: 1. SCAR other than DRESS including erythema multiforme, Steven Johnson syndrome, toxic epidermal necrolysis, acute generalized exenthematous pustulosis, drug induced vasculitis. 2. Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of maculopapular drug rash epidemiology of drug involved systemic involvement ( as mentioned in RegiSCAR criterion) Tarc levelTimepoint: baseline 3-4 weeks 6-8 weeks 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Time taken for resolution of rash. development of hypothyroidism.Timepoint: 3-4 weeks 6-8 weeks 12 weeks | — |
Countries
India
Contacts
Public ContactDr M Sendhil Kumaran
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH
Outcome results
None listed