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To study effect of using chest down and back up position in children with lung injury of mild to moderate category as classified under Pediatric acute lung injury consensus guidelines.

Randomised control trial to study the efficacy of prone positioning in mild and moderate acute respiratory distress syndrome.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023891
Enrollment
134
Registered
2020-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Proning: Intervention group shall be placed in prone position for 16 hours and then taken in supine position for remaining 8 hours everyday .This process of proning will be stopped once

Sponsors

Rainbow Children Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 1 month to 18 years diagnosed as mild or moderate Pediatric acute respiratory distress syndrome and is on invasive mechanical ventilation for at least 6 to 12 hours and anticipated need to continue mechanical ventilation for at least next 24 hours

Exclusion criteria

Exclusion criteria: Children who do not qualify in the definition in the definition of Pediatric acute respiratory distress syndrome as per PALICC guidelines or who are not on invasive mechanical ventilation Hemodynamically unstable patients,patients who require peritoneal dialysis or hemodialysis,patients with increased intraabdominal pressures with risk of abdominal compartment syndrome,burns cases more than 20 percentage,raised intracranial pressure,serious facial trauma,air leaks with chest tube such that prone position not possible,chronic respiratory failure or non invasive mechanical ventilation

Design outcomes

Primary

MeasureTime frame
To study improvement in oxygenation index at the end of 24 hours of prone positioning in mild and moderate Pediatric acute respiratory distress syndromeTimepoint: At the end of 24 hours of randomisation—

Secondary

MeasureTime frame
To study effect of prone positioning in mild and moderate Pediatric acute respiratory distress syndrome on other outcome parameters like mortality,ventilator days,length of PICU stay, ventilator free days at day 28 ,need for sedation . Timepoint: 2 year of study;To study effect of proning on trends of driving pressures and mechanical power in Pediatric acute respiratory distress syndromeTimepoint: 2 years of study—

Countries

India

Contacts

Public ContactDr Farhan Shaikh

Rainbow children hospital

farhanshaikh74@gmail.com9866007602

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026