Comparison of a drug in two different routes for ultrasound guided erector spinae block in adult females undergoing modified radical mastectomy surgery for breast cancer

Comparison Of Intravenous Dexamethasone With Perineural Dexamethasone Added As Adjuvant To 0.5% Ropivacaine For Ultrasound Guided Erector Spinae Block In Adult Females Undergoing Modified Radical Mastectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/023881

Enrollment

Registered

2020-03-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: Comparison of intravenous dexamethasone with perineural dexamethasone added as adjuvant to 0.5% ropivacaine for ultrasound guided erector spinae block in adult females undergoing modifi

Eligibility

Inclusion criteria

Inclusion criteria: This study will be conducted on adult females of age 18-65 years of American Society of Anaesthesiologists(ASA) physical status I or II,weighing 40-85 kgs scheduled for elective MRM surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Contraindications to blocks (like patients with coagulopathy or taking anticoagulants and local infection at the site of needle insertion) or recent neurological deficit. 2.Patients with history of hypersensitivity or allergy to drugs used in the study. 3.Patients suffering from cardiac,renal,hepatic and respiratory insufficiency.

Design outcomes

Primary

Measure	Time frame
To compare the duration of analgesia using perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomyTimepoint: 72 hours postoperative period	—

Secondary

Measure	Time frame
To compare the duration of sensory block by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomyTimepoint: 72 hours postoperative period;To compare the quality of pain control by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy using Numerical Rating Scale(NRS)Timepoint: 72 hours postoperative period	—

Measure

Time frame

To compare the duration of sensory block by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomyTimepoint: 72 hours postoperative period;To compare the quality of pain control by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy using Numerical Rating Scale(NRS)Timepoint: 72 hours postoperative period

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Countries

India

Contacts

Public ContactGokila D

Vardhman Mahavir Medical College and Safdarjung Hospital

kapgup11@yahoo.co.in9811859019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026