A study to compare effects of lactic acid, mandelic acid and Trichloroacetic acid in dark circles around eyes.

A comparative study of efficacy and safety of 15% lactic acid peel vs 30% mandelic acid peel vs 10% Trichloroacetic acid peel in periorbital hypermelanosis.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/023862

Enrollment

Registered

2020-03-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L819- Disorder of pigmentation, unspecified

Interventions

Intervention1: 30% Mandelic acid: Applied within 20 seconds and left for 1 minute or till the end point of peel i.e. burning. Patient is followed up every 15 days for two and half months. Control Inte

Eligibility

Inclusion criteria

Inclusion criteria: Clinically diagnosed case of periorbital hypermelanosis. Age completed 18 years. Patient must have given written consent.

Exclusion criteria

Exclusion criteria: pregnant women. Women Who intent to become pregnant. Active infection in treatment area. Allergy to chemical peels constituent. Insufficient sun protection.

Design outcomes

Primary

Measure	Time frame
Decrease in hyperpigmentationTimepoint: Patient is followed up every 15 days for two and half months.	—

Secondary

Measure	Time frame
Erythema Burning Secondary infection Hypo or hyperpigmentation ScarringTimepoint: Patient is followed up every 15 days for two and half months.	—

Countries

India

Contacts

Public ContactDr Ashish Deshmukh

MGM medical college and hospital

ashish7557@gmail.com9422213292

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026