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Comparison of a specific drug for two different time durations for treatment of Neurocysticercosis in children

Fourteen days versus twenty eight days course of Albendazole therapy for Neurocysticercosis in children: An open labelled, two arm, randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023792
Enrollment
60
Registered
2020-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B690- Cysticercosis of central nervous system

Interventions

Intervention1: Fourteen days Albendazole therapy: Albendazole (15 mg/kg/day) for 14 days plus standard treatment, maximum daily dose being 800 mg. Control Intervention1: Twenty eight days Albendazole

Sponsors

Narain Das Vaswani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 1-14 years newly diagnosed with active neurocysticercosis will be enrolled.

Exclusion criteria

Exclusion criteria: 1. Children who have received albendazole or diagnosed with NCC in preceding 3 months. 2. Children with intellectual disability or global developmental delay, coexisting neurodegenerative/neurometabolic or any other structural pathology. 3. Children with recognized progressive neurological illness. 4. Children with renal, pulmonary, cardiac or hepatic dysfunction.

Design outcomes

Primary

MeasureTime frame
Proportion of children with resolution of active lesion (Active lesion was considered to be resolved when either there was complete disappearance of lesion or when T2 hyperintensity within the core of the lesion has become either isointense or hypointense with or without blooming effect on GRE image) at 6 month follow up scan.Timepoint: 6 months

Secondary

MeasureTime frame
Duration to seizure recurrenceTimepoint: One week to six months

Countries

India

Contacts

Public ContactAnkit Singla

Pt. B.D. Sharma PGIMS Rohtak

ndvaswani@hotmail.com9034428284

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026