Health Condition 1: R798- Other specified abnormal findingsof blood chemistry
Conditions
Interventions
Intervention1: Intravenous Fluids Administration: Subjects will be allocated either of the two maintenance fluids (isotonic:0.9% NaCl with 5% dextrose OR hypotonic fluid: 0.45% NaCl with 5% dextrose)
Sponsors
Lamphrang Nongtri
Eligibility
Inclusion criteria
Inclusion criteria: All infants between 1 month to 1 year of age,hospitalized and who need maintenance intravenous fluid for atleast 24 hours
Exclusion criteria
Exclusion criteria: 1. Signs of dehydration or shock at presentation 2. Severe acute malnutrition( weight for height 3. Children with congestive heart failure,renal failure,cirrhosis of liver,nephrotic syndrome,severe burns,raised intracranial pressure,suspected case of diabetes mellitus,diabetes insipidus and congenital adrenal hyperplasia. 4. Children who are receiving drugs that alter plasma sodium levels such as furosemide,vasopressin and mannitol. 5. Surgical(post operative) patients and those with neurosurgical disorders. 6. Children who have received IV fluid therapy prior to hospitalization to our hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be incidence of hyponatraemia(defined as serum sodium level less than 130mEq/L),24 hours after initiation of therapy.Timepoint: 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Mean serum sodium level 24 hours after initiation of therapy 2.Development of hypernatremia,defined as serum sodium level more than 150 mEq/L 3.Acid base abnormalities(metabolic acidosis and metabolic alkalosis) 4.Signs of fluid overload.Timepoint: 24 hours | — |
Countries
India
Contacts
Public ContactLamphrang Nongtri
Head of Department Pediatrics, Mentor
Outcome results
None listed