Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: southwest technology elasto gel frozen gloves and socks: In dominating hand and foot we will apply frozen gloves & socks (elasto gel temp is -10 to -20 degrees Celsius).
for prevention
Sponsors
Tata memorial hospita
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult >18yrs. 2.Prescribed Paclitaxel as a single or multimodal treatment for breast cancer diagnosis for 12 weeks. 3.No disorders of the nails or skin of the hand at the start of treatment 4.Able to provide informed consent in English/Hindi/Marathi/Bengali. 5.No baseline arteriovenous thrombosis/claudication or hypersensitivity disorder, allergy.
Exclusion criteria
Exclusion criteria: 1. Previous treatment with taxane chemotherapy 2. Medical history of Reynaudâ??s phenomenon, distal metastases,ungual pathology,arteriopathy, cold intolerance, peripheral neuropathy of any grade. 3. Not fit for participation in the opinion of the treating oncologist/physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study will investigate the feasibility and safety of cryotherapy, in the form of frozen gel gloves & socks, with respect to the prevention of paclitaxel-induced peripheral neuropathy in cancer patients.Timepoint: to check if the frozen gloves(temp -10 deg to -20 deg) which is to be used in the study is safe and tolerable by the patient or not at the time of administration of paclitaxel injection infusion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To assess the efficacy of frozen gel gloves & socks, with respect to the prevention of paclitaxel-induced peripheral neuropathy in cancer patients. 2) To assess the incidence and severity of peripheral neuropathy in the ice treated limb as compared to nontreated side prevention of paclitaxel induced peripheral neuropathy. Timepoint: prevention of periphral neuropathy after 2nd cycle upto 12th cycle of weekly paclitaxel injection infusion | — |
Countries
India
Contacts
Public Contactvaishali anandrao chalke
Tata Memorial Centre
Outcome results
None listed