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To evaluate the efficacy and safety of regional block of the abdomen( between 2 muscles) using ultrasound guidance after laparoscopic nephrectomy surgery - a clinical trial

To evaluate the efficacy and safety of continuous quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy â?? A Randomised controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023760
Enrollment
64
Registered
2020-03-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Quadratus lumborum block type 3: After completion of surgery, following all aseptic precautions, a curvilinear low frequency ultrasound(US) probe (LOGIQe, GE Healthcare, China) will be

Sponsors

All India Institute of Medical Sciences Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: After approval from institutional ethical committee and written informed consent, patients belonging to American Society of Anaesthesiologists (ASA) physical status grade I and II, 18-65 years of age scheduled for laparoscopic nephrectomy will be included in the study.

Exclusion criteria

Exclusion criteria: Patients with infection at the block site, coagulation disorders, morbid obesity (BMI >40 kg/m2), allergy to local anaesthetic agent, major cardiac-respiratory disorders, severe renal or hepatic dysfunction, pre-existing neurological de�cit, psychiatric illness and excessive bleeding during the procedure will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
To compare total fentanyl consumption (as rescue analgesic) during first 48 hours postoperativelyTimepoint: To compare total fentanyl consumption (as rescue analgesic) during first 48 hours postoperatively

Secondary

MeasureTime frame
a) To compare Numerical Rating Scale (NRS) pain score b) To compare the duration of analgesia (time for request of first rescue analgesia after surgery) c) To compare patient satisfaction score d) To measure the CRP levels as a surrogate marker of stress response and pain transmission e) To compare any complications/side effect of block, catheter and drug Timepoint: NRS score - 0 hours,1,2,4,8,12,24,36 and 48 hours on rest and movement Time for first rescue analgesia after giving QL block Patient satisfaction score - Likert scale(1 to 5) CRP levels- pre operative 24 hours 48 hours Catheter related complications Catheter position - every 12 hours for misplacement/dislodgement

Countries

India

Contacts

Public ContactNidhi Jain

All India Institute of Medical Sciences, Jodhpur

nidzz11@gmail.com9950410569

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026