Health Condition 1: I958- Other hypotension
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-65 years Within 24 hours of ICU admission Acute Circulatory Failure â?? As defined by requirement of Vasoactive agents (in spite of adequate fluid resuscitation) for more than two consecutive hours to target MAP >65 mmHg or to a MAP considered to be optimal by treating physician
Exclusion criteria
Exclusion criteria: AKI on admission As defined by KDIGO guidelines if preadmission creatinine is available As per MDRD study calculation if preadmission creatinine is not available Non-index ICU admission Poor abdominal echogenicity Chronic kidney disease as defined eGFR less than 60 ml /min / 1.73m2 On Renal Replacement Therapy, Renal Transplant recipients, Single kidney patients,Renal donors,Known Renal Artery stenosis, Pregnancy, Kidney tumor, Known anatomical kidney abnormality Suspected Intra-abdominal hypertension, Obstructive uropathy, Urotrauma, Status post â?? Urological or Aortic surgery or Intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify if the parameters derived from renal Doppler ultrasound (RRI,PDU and their ratio) measured daily for first three days (initial value and its change over 72 hours) can predict development of Acute Kidney Injury (AKI) as defined by KDIGO criteria nTimepoint: 5 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Requirement of Renal Replacement Therapy Length of ICU stay Mortality at 28 days Number of days on vasopressor therapy Number of days on Mechanical ventilation Timepoint: As mentioned above | — |
Countries
India
Contacts
Department of Anesthesiology,Critical Care and Pain Medicine, AIIMS