Comparing blood products made in different test tubes in patients with bone loss

A comparative evaluation of T-PRF and PRF with alloplastic bone graft in the treatment of grade 2 furcation defects in chronic periodontitis â?? A Randomized controlled clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/03/023741

Enrollment

Registered

2020-03-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R938- Abnormal findings on diagnostic imaging of other specified body structures

Interventions

Intervention1: T-PRF with alloplastic bone graft: use of T-PRF with alloplastic bone graft in the treatment of grade 2 furcation defects Control Intervention1: PRF with alloplastic bone graft: PRF wit

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients within the age group 30 to 50 years Patient having at least one Glickman Grade II furcation defects in the mandibular first and second molars with >=3 mm horizontal probing depth Patients who had not taken antibiotics and chemotherapeutic drugs an within 6 months that may modify the result of periodontal therapy

Exclusion criteria

Exclusion criteria: o Patients having habits such as smoking and chewing tobacco o Women who are pregnant or lactating o Mobile tooth o Endo-perio lesions o Patients with bruxism

Design outcomes

Primary

Measure	Time frame
Site specific plaque index (PI) Modified sulcus bleeding index (mSBI) Probing depth (PD) from the gingival margin Clinical attachment level (CAL) along with gingival marginal level (GML) Radiographic measurements using CBCT Timepoint: Site specific plaque index (PI) Modified sulcus bleeding index (mSBI) Probing depth (PD) from the gingival margin Clinical attachment level (CAL) along with gingival marginal level (GML) Radiographic measurements using CBCT	—

Measure

Time frame

Site specific plaque index (PI) Modified sulcus bleeding index (mSBI) Probing depth (PD) from the gingival margin Clinical attachment level (CAL) along with gingival marginal level (GML) Radiographic measurements using CBCT Timepoint: Site specific plaque index (PI) Modified sulcus bleeding index (mSBI) Probing depth (PD) from the gingival margin Clinical attachment level (CAL) along with gingival marginal level (GML) Radiographic measurements using CBCT

—

Secondary

Measure	Time frame
Preservation and maintenance of the health of teeth and periodontal structures is the potential benefit of this treatment.Timepoint: Baseline, 6months	—

Countries

India

Contacts

Public ContactDr Lakshmi

Manipal College Of Dental Sciences

pratibha.pk@manipal.edu9448724121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026