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Comparison of low and high density local anaesthetic agent for one limb surgery

Comparative evaluation of low dose hypobaric and hyperbaric bupivacaine for surgeries under unilateral spinal anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023717
Enrollment
60
Registered
2020-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S870- Crushing injury of knee Health Condition 2: S878- Crushing injury of lower leg Health Condition 3: S823- Fracture of lower end of tibia Health Condition 4: S82- Fracture of lower leg, including ankle Health Condition 5: S910- Open wound of ankle Health Condition 6: M972- Periprosthetic fracture around internal prosthetic ankle joint Health Condition 7: S930- Subluxation and dislocation of ankle joint Health Condition 8: S831- Subluxation and dislocation of knee Health C

Interventions

Intervention1: comparison of hypobaric Bupivacaine and hyperbaric bupivacaine for unilateral spinal anaesthesiae: In the intervention Unilateral spinal anaesthesia will be given with hyperbaric bup

Sponsors

Punjab Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Sixty patients of either sex, ASA grade I-III, aged between 18-65 years posted for unilateral lower limb surgeries. Procedures lasting for maximum duration of 60 minutes will be included.

Exclusion criteria

Exclusion criteria: 1. Hypovolemia, 2. Preexisting Neurological Disease, 3. Coagulation Disorders, 4. Administration of thromboprophylaxis less than eight hours prior to the surgery 5. Infection At The Puncture site, 6. Agitation And Delirium,

Design outcomes

Primary

MeasureTime frame
1. Efficacy of the Blockade 2. Haemodynamic Stability 3. Anaesthesia onset and offset time, 4. Patient satisfaction Timepoint: 1.Immediately after spinal anaesthesia 2. At 15 min interval during surgery 3.At the end of surgery

Secondary

MeasureTime frame
Side effects related to drugs ie Bradycardia Hypotension Nausea and VomitingTimepoint: 1. During surgery 2. 2 hours after completion of surgery

Countries

India

Contacts

Public ContactArwinderPal Singh

Punjab institute of medical sciences, Jalandhar

docsaasha2009@gmail.com07973449563

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026