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Improvement in arthritis following improvement in oral health by cleaning of the teeth

Evaluating the influence of non surgical periodontal treatment on the clinical and biochemical measures of rheumatoid arthritis:A randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023692
Enrollment
34
Registered
2020-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified

Interventions

Intervention1: Non surgical periodontal treatment: Subjects in the intervention group will be given non surgical periodontal treatment which is full mouth disinfection with in 24 hrs,standard disease

Sponsors

Government Dental college and Research InstituteBangalore
Lead Sponsor
Bangalore Medical college and Research InstituteBangalore
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects in the age group of 30-60 years. 2. Both male and female subjects. (Inclusive) 3. Subjects with Rheumatoid arthritis (diagnosed based on 2010 ACR/EULAR Classification Criteria for RA). 4. Periodontitis (Stage I and stage II periodontitis, Grade A and B.) as per 2017 classification of periodontal disease and conditions)

Exclusion criteria

Exclusion criteria: 1. Subjects with Periodontal abscess and Endodontic-Periodontal lesions, Necrotizing Periodontal diseases, or periodontitis as a manifestation of systemic disease. 2. Subjects with tobacco consumption in any form. 3. Subjects with systemic diseases or conditions affecting the periodontal supporting tissues. 4. Subjects with systemic disease and conditions affecting the course of Rheumatoid arthritis. 5. Subjects who had received periodontal therapy in the last six month. 6. Subjects who had received antibiotics 3 months preceding the examination or may require antibiotic therapy during the study period. 7. Subjects with neoplastic conditions or severe systemic infections like HIV, HEPATITIS B etc. 8. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Primary out come: Assessment of serum CRP and ACPA level, Timepoint: Primary out come: Assessment of serum CRP and ACPA level at baseline,2 months—

Secondary

MeasureTime frame
DAS 28 score, probing pocket depth and clinical attachment level,plaque score , bleeding on probingTimepoint: At baseline,2 months,4 months and 6 months.—

Countries

India

Contacts

Public ContactDrSmithaK

Government Dental college and Research Institute,Bangalore

periosmitha@gmail.com9449630572

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026