Health Condition 1: P059- Newborn affected by slow intrauterine growth, unspecified
Conditions
Interventions
Intervention1: Full Volume Feeding: Age ml/kg/day
D1 80
D2 100
D3 120
D4 140
D5 160
D6 180
D7 180-200
Control Intervention1: Small Volume Feeding: Age ml/kg/day
D1 20
D2 40
Sponsors
Banaras Hindu University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Birth weight between 1000-1499 g
Exclusion criteria
Exclusion criteria: 1.Hemodynamic instability 2.Delivery room resuscitation >1 minute accompanied by neonatal encephalopathy 3.Inability to feed orally due to severe respiratory distress or sickness 4.Reversal of end-diastolic flow on maternal ultrasound 5.Major congenital malformation 6.Failure to obtain informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of extrauterine growth restriction defined as growth parameters (weight, length, head circumference) for postmenstrual age below or equal to 10th centile (Z score below -1.28) as per Intergrowth 21st referenceTimepoint: Hospital discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Late onset sepsis, defined as per European Medicines Agency (modified) 2. Feeding intolerance 3. Necrotizing enterocolitis defined as Bells stage 2 or 3 4. Time to regain birth weight 5. Time to achieve full volume feeding 6. Mortality before hospital discharge 7. Duration of hospital stay 8. Rate of exclusive breastfeeding at hospital discharge 9. Physical growth-weight, length and head circumference at hospital discharge, 3 months, 6 months and 1 year Timepoint: Hospital discharge for outcomes 1 to 8 One year for outcome 9 | — |
Countries
India
Contacts
Public ContactShivani Deep Singh
Banaras Hindu University
Outcome results
None listed