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Comparative study between two local anaesthetic agents as a cocktail injection, in immediate post operative pain relief and mobilisation in Knee Replacement patients.

Role of periarticular injection of cocktail in immediate post op analgesia and rehabilitation in patients undergoing Total Knee Arthroplasty(TKA)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/03/023673
Enrollment
46
Registered
2020-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: â?¢ Local infiltration injection of a mixture COCKTAIL(Total-64ml) comprising of 0.5% or Bupivacaine 20 ml OR 0.5% Ropivacaine 20ml, Tranexamic acid 20 ml(2g/20ml), Butorphanol 1ml(1mg

Sponsors

Yenepoya medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing elective total knee arthroplasty consenting to be included in the study

Exclusion criteria

Exclusion criteria: 1.Active inflammatory/ connective tissue disease (eg., Rheumatoid arthritis) 2.Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) or local anesthetic agents 3.Previous major surgery on the knee on which TKA was performed 4.Patients with post traumatic secondary arthritis knee

Design outcomes

Primary

MeasureTime frame
Periarticular injection reduces the post operative pain in patients undergoing TKA, reduces hospital stay, improve functional outcome and lead to early discharge of patients from hospital. outcome will be assessed by using, VAS ASSESSMENT (1-10) LIKERT SCALE STRAIGHT LEG RAISING TIME(seconds) KNEE MOVEMENTS(degrees) Timepoint: at 12 hours and 24 hours after the surgery—

Secondary

MeasureTime frame
early knee mobilisation - KNEE MOVEMENTS(degrees)Timepoint: at 12 hours and 24 hours after the surgery—

Countries

India

Contacts

Public ContactNINAD KANGOKAR

yenepoya medical college, Mangalore

savithshetty2007@reiffmail.com9686413837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026