Health Condition 1: B- Imaging Health Condition 2: 4- Measurement and Monitoring
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Readiness for weaning from mechanical ventilation as assessed by Recovery from the cause of respiratory failure, Stable haemodynamic status with no requirement for vasopressors, Fully conscious, Glasgow Coma Scale Less than or equal to 14, Fraction of inspired oxygen (Fio2) less than0.5,positive end expiration pressure (PEEP) Less than or equal to 5cm H2O, respiratory rate less than 30, partial pressure of oxygen (PaO2)/FiO2 more than 200
Exclusion criteria
Exclusion criteria: 1. Pneumothorax, pleural effusion, collapse, fibrosis 2. History of neuromuscular disease, diaphragmatic palsy, thoracic surgery, any mass or mechanical factor in chest or abdomen 3.Tracheostomy tube in situ 4. Pregnancy, ascites, morbid obesity 5. Surgical dressings over the right lower rib cage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of diaphragmatic excursion and diaphragmatic thickness fraction by ultrasonography predicting weaning outcome in patients on mechanical ventilation.Timepoint: Patient hemodynamically stable, ventilating on T-piece for 1 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| Better predictor of diaphragmatic excursion or diaphragmatic thickness fractionTimepoint: After extubation;compare diaphragmatic rapid shallow breathing index (RSBI) with clinical RSBITimepoint: before extubation;correlation between diaphragmatic dysfunction with reintubationTimepoint: within 48 hours of extubation | — |
Countries
India
Contacts
Vardhman Mahavir medical college and Safdarjung hospital