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Assessment of diaphragmatic parameters using ultrasound for predicting weaning outcome in patients on mechanical ventilation in intensive care unit setting

Ultrasonographic assessment of diaphragmatic parameters for predicting weaning outcome in patients on mechanical ventilation in intensive care unit setting

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/02/023662
Enrollment
50
Registered
2020-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B- Imaging Health Condition 2: 4- Measurement and Monitoring

Interventions

Sponsors

Vardhman Mahavir Medical College and Safdarjung Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Readiness for weaning from mechanical ventilation as assessed by Recovery from the cause of respiratory failure, Stable haemodynamic status with no requirement for vasopressors, Fully conscious, Glasgow Coma Scale Less than or equal to 14, Fraction of inspired oxygen (Fio2) less than0.5,positive end expiration pressure (PEEP) Less than or equal to 5cm H2O, respiratory rate less than 30, partial pressure of oxygen (PaO2)/FiO2 more than 200

Exclusion criteria

Exclusion criteria: 1. Pneumothorax, pleural effusion, collapse, fibrosis 2. History of neuromuscular disease, diaphragmatic palsy, thoracic surgery, any mass or mechanical factor in chest or abdomen 3.Tracheostomy tube in situ 4. Pregnancy, ascites, morbid obesity 5. Surgical dressings over the right lower rib cage

Design outcomes

Primary

MeasureTime frame
Diagnostic accuracy of diaphragmatic excursion and diaphragmatic thickness fraction by ultrasonography predicting weaning outcome in patients on mechanical ventilation.Timepoint: Patient hemodynamically stable, ventilating on T-piece for 1 hour

Secondary

MeasureTime frame
Better predictor of diaphragmatic excursion or diaphragmatic thickness fractionTimepoint: After extubation;compare diaphragmatic rapid shallow breathing index (RSBI) with clinical RSBITimepoint: before extubation;correlation between diaphragmatic dysfunction with reintubationTimepoint: within 48 hours of extubation

Countries

India

Contacts

Public ContactDr Vandana Talwar

Vardhman Mahavir medical college and Safdarjung hospital

Drvandanatalwar@gmail.com9811352251

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026