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Comparison of ropivacaine versus dexmedetomidine or ketamine in modified PECS II block in patients undergoing breast surgery: A Randomized trial

Efficacy of dexmedetomidine and ketamine as an adjuvant with ropivacaine in PECS II block among the patients undergoing modified radical mastectomy/ breast conservation surgery: A Randomized double blind controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023655
Enrollment
75
Registered
2020-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: not applicable: not applicable Control Intervention1: comparing 0.2% ropivacaine alone with dexmeditomidine 1 mcg/kg body weight or ketamine 1 mg/kg body weight in PECS 2 BLOCK in patie

Sponsors

All india institute of medical sciences patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Female population aged between 18-65 years 2) ASA I & II 3) Patients undergoing breast surgeries

Exclusion criteria

Exclusion criteria: Patient refusal Patients with underlying severe cardio-pulmonary compromise Morbid obesity BMI more than or equal to 35 Chest wall infiltration Presence of malignant breast mass in the field of block performance Pregnancy,lactation, dementia. Allergy to Local Anesthetic or adjuvants, Patients already on prescribed oral opioid analgesics or psychotropic agents Post radiation status of breast or axilla

Design outcomes

Primary

MeasureTime frame
To compare the total duration of post-operative analgesia and requirement of first rescue analgesia by the patient using an adjuvant (dexmedetomidine or ketamine) with ropivacaine in PEC II block undergoing breast surgeriesTimepoint: 48 hours—

Secondary

MeasureTime frame
To determine the total amount of intra operative and post-operative opioid consumption To assess the nnumerical rating scale in 1,2,4,6,1,18,24,48 hours post operatively To assess the patient satisfaction score To measure the ramsay sedation score when patient is being shifted to PACUTimepoint: After 48 hours till discharge of the patients from hospital—

Countries

India

Contacts

Public ContactDr Rajnish Kumar

All India Institute of medical sciences patna

drraj76pmch@gmail.com7783865337

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026