A study to compare the effect of dexmeditomidine on block characteristics when given by two different route perineural and intravenous along with supraclavicular brachial plexus block with bupivacaine in upper limb surgery.

A comparative study of intravenous and perineural dexmedetomidine in supraclavicular brachial plexus block using 0.5%bupivacaine in upper limb surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023652

Enrollment

Registered

2020-02-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: intravenous dexmeditomidine along with supraclavicular brachial plexus block: A single dose PNS guided supraclavicular brachial plexus block will be given with 0.5% bupivacaine 2mg/kg d

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologist (ASA) grade I or II patients Scheduled for elective upper limb surgery below mid-humerus level AGE 18 - 60 Year Both gender

Exclusion criteria

Exclusion criteria: Peripheral neuropathy of upper limb Bleeding disorders, Infection at the injection site, Untreated pneumothorax, Patients on adrenoreceptor agonist or antagonist therapy, History of severe cardiac, respiratory, hepatic or renal disease, pregnancy Known hypersensitivity to the study drugs Patientâ??s refusal

Design outcomes

Primary

Measure	Time frame
1-onset and duration of sensory block 2-onset and duration of motor block 3- postoperative analgesic requirementTimepoint: 1-onset of sensory and motor block will be assessed from administration of block till the onset of effect 2- duration of motor and sensory block will be assessed from onset of block to the resolution of effect 3- postoperative analgesic requirements will be assessed from the end of the surgery to 24 hour post operative period	—

Measure

Time frame

1-onset and duration of sensory block 2-onset and duration of motor block 3- postoperative analgesic requirementTimepoint: 1-onset of sensory and motor block will be assessed from administration of block till the onset of effect 2- duration of motor and sensory block will be assessed from onset of block to the resolution of effect 3- postoperative analgesic requirements will be assessed from the end of the surgery to 24 hour post operative period

—

Secondary

Measure	Time frame
1-perioperative hemodynamic profile 2-sedation scoreTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactAMAL KRISHNA MISHRA

JAWAHARLAL NEHRU HOSPITAL AND RESEARCH CENTRE

drjayitaonnet@yahoo.in09439840119

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026