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Comparative study to see the effects of drug on incidence and severity of post operative sore throat

Comparative study to see the effects of different dosage of intracuff dexamethasone on incidence and severity of post operative sore throat - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023647
Enrollment
75
Registered
2020-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: assessment of reduction in post- extubation sore throat after administration of study drugs in the cuff of endotracheal tube (ETT) in patients requiring intubation: Dexamethasone in two

Sponsors

Department of anaesthesiology AIIMS Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. The population between age group of 18 year to 65 years, weighing 40-80 kg. 2. Patients belonging to ASA I or II. 3. Patients receiving general anaesthesia with endotracheal intubation for elective surgery

Exclusion criteria

Exclusion criteria: The study will exclude: 1. Patients with history of recent respiratory tract infection or sore throat. 2. History of neuromuscular disease. 3. Duration of tracheal intubation of 240 min and requiring more than one attempt for tracheal intubation. 4. Preoperative use of analgesics or steroids. 5. History of laryngeal or tracheal surgery or pathology 6. Any patients with diabetes mellitus and obesity will also be excluded.

Design outcomes

Primary

MeasureTime frame
Assessment of POST: The assessment of sore throat and hoarseness will be done at one hour, 6 hr and 24 hrs post extubation. Scoring system will be as follows: POST 0 - no sore throat 1 - Minimal sore throat 2 - Moderate sore throat 3 - Severe sore throat Timepoint: 1 h, 6 h, 24 h

Secondary

MeasureTime frame
HOARSENESS 0- No complaint of hoarseness 1- Minimal change in quality of speech (minimal hoarseness) 2- Moderate change in quality of speech (moderate hoarseness) 3- Gross change in the quality of speech (severe hoarseness) Timepoint: 1h, 6h, 24 h

Countries

India

Contacts

Public ContactBhavna Gupta

AIIMS hospital, Rishikesh

bhavna.kakkar@gmail.com8527686660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026