Health Condition 1: M058- Other rheumatoid arthritis with rheumatoid factor
Conditions
Interventions
Intervention1: Niruha Vasthi (medicated enema): Kshara Vasthi of 600 ml daily for 8 days per rectally
Control Intervention1: Not applicable: Not Applicable
Sponsors
Aswathy Y S
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of age group 20â??45 years irrespective of gender. 2. The patient having the clinical features of Amavata according to Ayurvedic classics 3. Patient who fulfil ACR criteria. 4. Patients identified with presence of Prevotella copri and Prevotella histicola from their fecal samples. 5. Patient of RA having chronicity 6. Patients who are eligible for Vasthi
Exclusion criteria
Exclusion criteria: 1. Patients having severe crippling deformities 2. Patients suffering from paralysis 3. Diagnosed cases of neoplasm of spine, gout, traumatic arthritis, and pyogenic osteomyelitis 4. Patients diagnosed with associated cardiac disease, pulmonary tuberculosis, diabetes mellitus, inflammatory bowel disease, malignant hypertension, renal function impairment. 5. Recent use of antibiotic therapy ( 6. Pregnant women and lactating mother
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective parameters 1. Clinical signs and symptoms will be assessed by Clinical Disease Activity Index (CDAI) 2. Activities of patient will be assessed by Patient Activity Scale (PAS) 3. Activity of disease will be assessed by Disease Activity Scale (DAS28) Objective parameters: 1. ACR/EULAR criteria 2. Isolation and identification of Prevotella copri and Prevotella histicola from Human Faecal microbes on 9th and 25th day of treatment. Timepoint: On 9th and 25th day of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicableTimepoint: Not Applicable | — |
Countries
India
Contacts
Public ContactDr Anandaraman P V
Amrita School of Ayurveda Amritapuri Amrita Vishwa Vidyapeetham India
Outcome results
None listed