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Long term evaluation of success and survival Of Immature Permanent Teeth Treated with Different treatment Protocols

Clinical, CBCT Based Radiographic assessment and Biomechanical analysis Of Immature Permanent Teeth Treated with Different Regenerative Protocols: A multi arm Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023603
Enrollment
60
Registered
2020-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Regenerative endodontic treatment with injectable Platelet rich fibrin: 10 mL blood will be collected in a sterile polyethylene terephthalate plastic tubes without anticoagulant which w

Sponsors

maulana Azad Institute of Dental Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Immature necrotic permanent teeth showing clinical and radiographic diagnosis of pulp necrosis with or without periapical involvement 2. Radiographically the tooth has an open apex ( > 1mm) 3. Age of the patient: 13-30 years

Exclusion criteria

Exclusion criteria: 1. Medical conditions that would contraindicate endodontic treatment (eg, acute systemic disease and abnormalities in host defense), 2. Remaining crown/root structure with questionable restorability 3. Teeth with vertical fractures 4. Periodontally involved teeth 5. Lack of patient and parent cooperation.

Design outcomes

Primary

MeasureTime frame
the resolution of clinical symptoms and the evidence of osseous healing on CBCT evaluationTimepoint: 6,12,18 months

Secondary

MeasureTime frame
Increase in root wall thickness, increase in root length and decrease in apical diameter on CBCT evaluationTimepoint: 6,12,18 months

Countries

India

Contacts

Public ContactDr Sudha Yadav

Maulana Azad Institute of Dental Sciences, New Delhi

ruchika.roongta@gmail.com9582948894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026