Health Condition 1: K746- Other and unspecified cirrhosis ofliver
Conditions
Interventions
Intervention1: Large Volume paracentesis: 5 litres of Ascitic fluid will be taken out in the patients of cirrhosis with ascites and acute kidney injury
Control Intervention1: Patients on standard t
Sponsors
KIIT University
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >18 ,consent giving to participate 2.All consecutive hospitalized patients of cirrhosis with ascites and AKI (all etiologies of cirrhosis will be included) . 3.Diagnosis of the patients will be made on the basis of LFTs, imaging, upper GI endoscopy, ascitic fluid analysis and liver biopsy if needed, 4.Grade 2 & 3 ascites.(international ascites club )2 (2)EASL practice guidelines on management of ascites ,SBP,HRS in cirrhosis ,2010.
Exclusion criteria
Exclusion criteria: 1.Refusal to participate 2.Overt Hepatic Encephalopathy, Active Upper GI Bleed, Chronic Kidney Disease Stage-4, Spontaneous Bacterial Peritonitis, Hepatocellular Carcinoma, Hepatic venous outflow obstruction, HIV, Non Cirrhotic Portal Hypertension, portal venous thrombosis. 3.Ascites due to other causes like tuberculosis, constrictive pericarditis, etc. 4.Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease Heart rate, decrease in Mean arterial pressure, increased creatinine clearance, increase in urinary output, increase in plasma renin decrease in S. Creatinine Timepoint: All the above parameters will be checked on day 1, day 3, day 5. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Renal resistive indexTimepoint: 5 days | — |
Countries
India
Contacts
Public ContactDr Anirudh Tiwari
Kalinga Institute of Medical sciences
Outcome results
None listed