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To study the effectiveness of Siddha treatment in patients with psoriasis with respect to gene (HLA-Cw6) and inflammatory mediators

Clinical and patient reported outcomes in patients treated with Agasthyar kulambu, Vetpalai thailam, and Sivanar vembu kuzhi thailam for psoriasis with respect to HLA-Cw6 allele status and inflammatory cytokines â?? a pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/02/023597
Enrollment
30
Registered
2020-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L400- Psoriasis vulgaris

Interventions

None listed

Sponsors

Directorate of Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both sexes and age above 18 years, patients with moderate to severe psoriasis (PASI score >10), patients with no systemic therapy for past four weeks or topical therapy for past two weeks

Exclusion criteria

Exclusion criteria: Pregnant and lactating woman, coexisting eczema or lichen planus, patients on any systemic drugs known to exacerbate psoriasis, patients who are on any other treatment for psoriasis.

Design outcomes

Primary

MeasureTime frame
Number of patients in RemissionTimepoint: At the end of 3 months of treatment—

Secondary

MeasureTime frame
Adverse drug reactions observedTimepoint: During the 3 months of treatment period;Improvement in the patient reported outcomes in terms of Dermatology Life Quality Index, Psoriasis Disability Index and Pittsburgh Sleep Quality IndexTimepoint: During the 3 months of treatment period;Reduction in blood inflammatory markers after the treatmentTimepoint: At the end of 3 months of treatment—

Countries

India

Contacts

Public ContactAmruth Kiran

Melaka Manipal Medical College

bodh.akb1989@gmail.com9901609651

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026