Skip to content

To study the effectiveness of a newer anaesthetic procedure/block i.e. paravertebral block in breast cancer surgeries for pain relief.

The efficacy of paravertebral block evaluated by pain related biomarkers and reactive oxygen species (ROS) following surgery for breast cancer: A randomised controlled study.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023594
Enrollment
40
Registered
2020-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Paravertebral block: Paravertebral space will be identified in lateral position with operative side up. Local anaesthesia is administered 2.5cm lateral to midline between T4 to T6. An

Sponsors

Karnataka Institute of Medical Sciences Hubballi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing breast cancer surgery with/without lymph node dissection

Exclusion criteria

Exclusion criteria: Age ASA ââ?°Â¥ IV Bleeding disorders Contraindications or allergy to any of study drugs including local anaesthetics, NSAIDs. Infection at the paravertebral insertion site. Pregnancy or breast feeding, obesity. Any hearing or visual loss, any neurological or mental disorder. Patients undergoing redo surgery. Patient with significant co-morbid illness influencing the measurement of biomarkers like Wilsonââ?¬•s disease, Cushingââ?¬•s disease etc.

Design outcomes

Primary

MeasureTime frame
Visual analogue scaleTimepoint: Baseline,2hours, 24 hours and 48hours

Secondary

MeasureTime frame
Ceruloplasmin, Lipid peroxides, immune circulating complexesTimepoint: Baseline, 24 hours and 48hours

Countries

India

Contacts

Public ContactMilon Vasant Mitragotri

Karnataka Institute Of Medical Sciences

milon.mitragotri4@gmail.com7406796763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026