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Intrauterine infusion of GCSF in Infertile women with thin endometrium

"Effect of intrauterine instillation of Granulocyte colony stimulating factor on thin endometrium in infertile women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023570
Enrollment
60
Registered
2020-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: GCSF: Dose:300mcg/ml Route:Intrauterine frequency:once at the time of trigger for IUI Control Intervention1: NIL: NIL

Sponsors

ESI PGIMSR BasaidarapurNDelhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Women with primary and secondary infertility undergoing natural/Controlled ovarian Stimulation Cycle with thin endometrium less than 7mm at the time of HCG trigger. ï?? 2. Infertile women with previously cancelled cycle because of thin unresponsive endometrium

Exclusion criteria

Exclusion criteria: 1. Endocrine Disorder. ï?? 2. History of haematological disease. 3. Congenital or acquired uterine anomaly. ï?? 4. Contraindication for GCSF treatment (past or present malignancy, renal insufficiency, liver dysfunction).

Design outcomes

Primary

MeasureTime frame
Endometrium thickness of greater than 7 mm after 36 to 40 hours of intra uterine instillation of Granulocyte colony stimulating factor.Timepoint: 36 to 40 hours.—

Secondary

MeasureTime frame
1) Occurrence of biochemical pregnancy after 2 weeks (urinary Pregnancy test positive) and clinical pregnancy (presence of intrauterine gestational sac on TVS) at 6weeks, during the follow up after the intrauterine instillation of GCSFTimepoint: 2 week and 6 week.—

Countries

India

Contacts

Public ContactNEELAM RAJPUROHIT

ESI PGIMSR Basaidarapur,New Delhi

dr.sanjana297@gmail.com9873690297

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026