FindTrial
Sign In

Comparison of two drugs for luteal phase support in IVF cycles

Comparison of efficacy and safety of GnRH agonist with low dose hCG for luteal phase support in women undergoing GnRH agonist triggered antagonist IVF cycles :randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023552
Enrollment
120
Registered
2020-02-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified

Interventions

Intervention1: GnRH agonist: injection leuprolide Acetate 0.5 mg s/c for luteal support starting from day 3 of oocyte pick up then alternate day, total 5 doses (day 3,5,7,9 and 11 of oocyte pickup, ta

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. FSH less than and equal to 12 IU/L 2. AMH more than and equal to 1.5 ng/ml 3. BMI 18 to 30 Kg/ m2 4. E2 more than 2500 pg/ml on the day of ovulation trigger

Exclusion criteria

Exclusion criteria: 1. More than and equal to 2 Previous IVF failures 2. Endometriosis 3. Hydrosalpinges (unilateral/bilateral) 4. Uterine factor unfavorable for implantation (adenomyosis, intrauterine adhesions, thin endometrium, fibroids) 5. More than 20 oocytes retrieved

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate Timepoint: To compare GnRH agonist with low dose hCG for luteal phase support among GnRH agonist triggered antagonist cycles in terms of clinical pregnancy rate—

Secondary

MeasureTime frame
1. Hormonal dynamics (E2,P4,LH) after oocyte retrieval 2. Implantation Rate 3. Ongoing pregnancy rate 4.OHSS rate 5.Miscarriage rate Timepoint: 2 years—

Countries

India

Contacts

Public ContactDr Reeta Bansiwal

AIIMS

drreetabansiwal@gmail.com9899893522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026