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comparison between ropivacaine and Ropivacaine Dexmedetomidine in surgical wound infiltration in PSRS surgery

Comparison of dexmedetomidine as an adjuvant with Ropivacaine versus Ropivacaine alone for continuous wound infiltration in patients undergoing Proximal Spleno-Renal Shunt (PSRS) surgery : A Prospective randomized control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023543
Enrollment
60
Registered
2020-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: subcutaneous infiltration of ropivacaine and Dexmedetomidine at surgical wound site: During surgical wound closer multi hole catheter will be placed by the operating surgeon in subcutan

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients 18 years and above; 2) ASA physical status I & II; 3) Patients undergoing PSRS surgery, 4)Patients operated with thoraco-abdominal incision.

Exclusion criteria

Exclusion criteria: 1.)Patients refusal to have catheter; 2) On systemic analgesic medication for some other ailment; 3) Patients with diabetic mellitus 4) Patient with cardiac disease 5) Base line heart rate less than 60 per minute. f) Known allergy to any of the study drugs

Design outcomes

Primary

MeasureTime frame
Reduction in Total fentanyl consumption in first 24 hours postoperative period.Timepoint: assessment of pain at 0,1,3,6,9,15,18 and 24 hours in postoperative period.

Secondary

MeasureTime frame
1)VAS at rest and on deep inspiration at 0,1,3,6, 9,15 ,18 and 24 hours post-operative period. 2.) Hemodynamic instability (Fall in blood pressure or heart rate more than 20% of base line) 3.) Total number of rescue antiemetic drug required in first twenty-four hours for Post-operative nausea and vomiting in both groups. 4.)incidence of Wound infection in first 5 days. Timepoint: first post operative day and upto uo to 5th postoperative day daily.

Countries

India

Contacts

Public ContactRAKESH KUMAR

AIIMS new delhi

drrakesh.kumar.akb@gmail.com01126593212

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026