A study to observe the effect of therapeutic doses of Diazepam among healthy individuals using stop signal reaction time

A randomized double-blinded placebo controlled trial to compare the effect of therapeutic doses (5mg, 10mg) of diazepam on response inhibition using stop signal reaction time (SSRT) in healthy volunteers.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023530

Enrollment

Registered

2020-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Diazepam: Diazepam 5mg OD, 10mg OD. Dose of 5mg and 10mg will have an interval of 3 weeks in between. Both the doses will be applied once after a baseline SSRT paradigm to each subject

Eligibility

Inclusion criteria

Inclusion criteria: Healthy individuals (male and female) of 20-50 years of age, without any neurological disorder Informed consent form will be signed by each subject before participation

Exclusion criteria

Exclusion criteria: Presence of any sleep related or behavioral disorder Usage of any neurotropic drug within last 7 days Habitual drug abuse

Design outcomes

Primary

Measure	Time frame
Stop Signal Reaction Time (SSRT)Timepoint: 8 weeks	—

Secondary

Measure	Time frame
Visual Analogue Scale (VAS) for scoring sedationTimepoint: 8 weeks	—

Countries

India

Contacts

Public ContactSwagata Sarkar

Institute of Neurosciences Kolkata

choudhurydrsupriyo@gmail.com9433106238

Outcome results