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Comparison of three drugs in reduction of pain because of anaesthetic drug.

Assessment and comparison of ketamine, dexamethasone and lignocaine in reduction of propofolâ??induced vascular pain. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023522
Enrollment
210
Registered
2020-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexamethasone vs ketamine vs lidocaine: Randomization will be done by computer generated random number tables and groups will be assigned by opening sealed sequentially numbered opaque

Sponsors

Department of anaesthesiology AIIMS Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The study will include patients belonging to ASA I, age group of 18 to 65 years, weighing 40-80 kg, receiving general anesthesia for elective surgery

Exclusion criteria

Exclusion criteria: Patients with known hypersensitivity to either lignocaine or dexamethasone or ketamine or propofol or egg or soyabean oil. Patients with a history of central nervous system or neuro-muscular disease or psychiatric illness. Patients with history of drug or alcohol abuse. History of chronic pain, or taking analgesics or sedatives preoperatively. Pregnant and lactating females. Patients with difficult venous access and small caliber veins. Patients requiring rapid sequence induction

Design outcomes

Primary

MeasureTime frame
1)To assess reduction in propofol induced pain by verbal rating score among groups pretreated with ketamine, dexamethasone and lignocaineTimepoint: every 30 seconds after giving propofol injection till patient is induced

Secondary

MeasureTime frame
To assess any complications such as thrombophlebitis, hyperglycemia or any adverse effects of drugsTimepoint: every 10 minutes till end of surgery

Countries

India

Contacts

Public ContactBhavna Gupta

AIIMS, Rishikesh

bhavna.kakkar@gmail.com8527686660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026