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Utility of whole blood based coagulation test (thrombelastography) in the assessment of abnormal bleeding conditions seen in severe infections.

Utility of thrombelastography in the assessment of sepsis induced coagulopathy in a tertiary care hospital in South India

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/02/023514
Enrollment
60
Registered
2020-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D65- Disseminated intravascular coagulation [defibrination syndrome]

Interventions

Intervention1: NIL: NIL

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All adult patients above the age of 18 years diagnosed with sepsis induced coagulopathy and admitted under the department of critical care medicine in Kasturba Hospital.

Exclusion criteria

Exclusion criteria: 1.Patients discharged against Medical advice. 2.Death within 24 hours of admission into ICU. 3.Patients with existing bleeding disorders or platelet function disorder. 4.Patients who is on oral anticoagulants and anti-platelet drugs which will confound the hemostatic status. 5.Patients with diagnosed immune deficiency (hereditary / acquired). 6.Patients with history of Transfusion in last three months. 7.Patients who are diagnosed with chronic liver disorder.

Design outcomes

Primary

MeasureTime frame
â?¢Compared to standard coagulation test, TEG may predict the in vivo hemostasis better.Timepoint: September 2021

Secondary

MeasureTime frame
1.Based on the diagnosis and categorization, developing a predictive score in the sepsis induced coagulopathy based on TEG might lead to a better patient care in future. 2.TEG may be useful in categorizing sepsis induced coagulopathy into hypo-coagulable bleeding type or prothrombotic organ failure type. Timepoint: September 2021

Countries

India

Contacts

Public ContactAshwinkumar Vaidya

Kasturba Medical College, Manipal Academy of Higher Education

shameeshastry@gmail.com9743489837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026