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Effect of High Protein Enteral Nutrition on Muscle Wasting in Critically Ill Patients

Effect of High Protein Normo-caloric Nutrition on Skeletal Muscle Wasting in Critically Ill Mechanical Ventilated Patients: A Randomized Double-Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023512
Enrollment
30
Registered
2020-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- critically ill patients Health Condition 2: J159- Unspecified bacterial pneumonia

Interventions

Intervention1: group1(SF): Group1(SF):high protein feed will contain calorie of 25kcal/kg/day with protein of 1.5gm/kg/day Control Intervention1: Group2(HF): Group2(HPF): standard feed will contain ca

Sponsors

All Indiaia Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients older than 18 years and anticipated to be intubated for longer than 48 hours and spend more than 7 days in critical care with enteral feed will be included in the study

Exclusion criteria

Exclusion criteria: 1) pregnancy 2)Trauma to the lower limb 3)History of neurological, neuromuscular or muscular wasting diseases 4)Vascular insufficiency or amputation of the lower limbs 5)Prolonged immobility prior to admission to intensive care 6)Unable to tolerate enteral feed 7)History of patients on long-term steroids

Design outcomes

Primary

MeasureTime frame
To measure the relationship between high protein diet and skeletal muscle wasting in critically ill patients during first week of ICU stayTimepoint: days- 1,3,5,7

Secondary

MeasureTime frame
To find correlation between muscle wasting and baseline Nutric score, organ dysfunction (SOFA), P/F ratio, comorbidities and sepsisTimepoint: days-1,3,5,7

Countries

India

Contacts

Public ContactBikash Ranjan Ray

AIIMS, New Delhi

castro.vetri6@gmail.com8778207402

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026