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Comparison Of two different forms of Steroid Therapy In Thyroid Eye Disease

Comparative Evaluation Of Peribulbar Steroid Therapy and Intravenous Pulse Steroid Therapy In Thyroid Eye Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023508
Enrollment
20
Registered
2020-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H052- Exophthalmic conditions

Interventions

Intervention1: Peribulbar Steroid Therapy: 4 injections of Peribulbar Triamcinolone acetonide (20mg dose
40mg/ml) will be administered at an interval of 2 weeks (week1,3,5,7) in each orbit at infero-temporal and supero-nasal quadrant, using a 26 Gauge half inch disposable needle. Control Intervention1: I

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Moderate-severe TED with modified Clinical Activity Score more than or equal to 4/10. 2. Stable thyroid disease 3. Age > 18years

Exclusion criteria

Exclusion criteria: 1. Diabetes Mellitus 2. Tuberculosis 3. Cancer 4. Sight-Threatening TED 5. Mild TED 6. Pregnancy 7. Uncontrolled hypertension 8. Psychosis

Design outcomes

Primary

MeasureTime frame
To compare improvement with Peribulbar steroid therapy and Intravenous pulse steroid therapy in terms of Modified Clinical Activity Score.Timepoint: at 2 months—

Secondary

MeasureTime frame
To study and compare complications of both, peribulbar and intravenous steroid therapy.Timepoint: At 2 months—

Countries

India

Contacts

Public ContactSushil Kumar

Maulana Azad Medical College

sushilkumar1958@yahoo.com9968604329

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026