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To evaluate the effect of intravenous ondansetron on blood pressure and heart rate on using Propofol in adult patients undergoing operation under general anaesthesia.

Evaluation of the effect of intravenous ondansetron on hemodynamics following induction with Propofol in adult patients undergoing surgery under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023497
Enrollment
80
Registered
2020-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Ondansetron: Giving intravenous Ondansetron(0.15mg/kg) 20 minutes before induction with propofol in adult patients undergoing surgery under general anaesthesia Control Inter

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists physical health status 1 and 2

Exclusion criteria

Exclusion criteria: 1)Cardiorespiratory,renal,hepatic or thyroid disorders 2) Pregnant Patients 3) Patients with difficult airway. 4) History of allergy to study drug. 5) Patients taking selective serotonin re-uptake inhibitors.

Design outcomes

Primary

MeasureTime frame
1)Incidence of hypotension in each group as determined by the number of patients( percentage) developing hypotension. 2)Degree of hypotension in each group at various time intervals after propofol administration.Timepoint: every 1 minute for 10 minutes after administration of propofol—

Secondary

MeasureTime frame
Changes in heartrate in each groupTimepoint: before induction and then every 1 minute for 10 minutes after administration of propofol;post operative nausea and vomitingTimepoint: 1 hour after surgery;Total dose of propofol usedTimepoint: During induction og general anaesthesia;Total Mephentermine dose usedTimepoint: after induction with propofol—

Countries

India

Contacts

Public ContactDr Munisha Agarwal

Maulana Azad Medical College

munisha.agarwal@gmail.com9718599241

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026