Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: Oral Haloperidol: First generation antipsychotic, Dose will be given as per the treating consultant based on efficacy and tolerability and the effects will be monitored at week 2, 4, 6,
Sponsors
Government Medical College and Hospital Chandigarh Sector
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with schizophrenia as per DSM-5 2) Total duration of illness shall be less than one year. 3) Age of the patients shall be between 18-45 years. 4) Drug naïve or not on any psycho tropics for 2 weeks. 5) Patients willing to participate and give consent or in case the patient lacks mental capacity, his/her nominated representative gives consent to participate.
Exclusion criteria
Exclusion criteria: 1) Patients who are not willing to give consent. 2) Pregnant and breast feeding patients. 3) Patients with co-morbid psychiatric illness and substance dependence. 4) Patients with severe medical and surgical illness. 5) Patients with high suicidal risk( Beckâ??s scale for suicidal ideation score >29) 6) Patients with history of sensitivity to haloperidol in the past. 7) Patients with history of depot antipsychotic administration in the past. 8) Patients with no response to haloperidol in the past or those reporting non-tolerability to the drug in the past. 9) Patients who had received ECT in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy and safety profile of oral and long acting injectable haloperidol in patients with first episode schizophrenia.Timepoint: Baseline, week 2, week 4, week 6, week 8, week 12 | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare quality of life in patients with first episode schizophrenia on oral and long acting injectable haloperidol. Timepoint: Baseline, week 4, week8, week 12 | — |
Countries
India
Contacts
Public ContactRamandeep Kaur
Government Medical College and Hospital, Chandigarh
Outcome results
None listed