A clinical study to check the anti bacterial effect of 0.5% herbal mouthwash and 0.2% chlorhexidine mouthwash in high decay prone individuals.

Comparative evaluation of antibacterial efficacy of 0.5% aqueous Piper betle leaves extract and 0.2% chlorhexidine as mouth rinse in high caries risk population Ã¢â?¬â?? an in vitro analysis and in vivo real time PCR study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023440

Enrollment

360

Registered

2020-02-19

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 0.5% Piper betle leaves etract: Comparing 0.5% Piper betle leaves extract and 0.2% chlorhexidine as mouthrinse for assessing the pH and buffering capacity of saliva, pH of plaque and qu

Eligibility

Inclusion criteria

Inclusion criteria: 1)Age group between 13-21yrs. 2)ASA I and II patients. 3)Patientshaving DMFT score greater than 5 and with at least one active carious lesion.

Exclusion criteria

Exclusion criteria: 1)Patients who used chemical anti-plaque agents and mechanical debridement procedures or were under antibiotics therapies. 2)Patients with development anomalies. 3)Mentally challenged patients. 4)Patients with xerostomia. 5)Patients undergoing fixed orthodontic appliance therapy.

Design outcomes

Primary

Measure	Time frame
Reduction in bacterial count in plaque and dentinal caries sample -Increase in pH of saliva -Increase in buffering capacity of saliva and plaque. Timepoint: 60 mins and 24 hrs	—

Secondary

Measure	Time frame
nillTimepoint: nill	—

Countries

India

Contacts

Public ContactDr L Vijay Amirtharaj

SRM Institute of Science and Technology

reasearchmaha@gmail.com044-22490526

Outcome results