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Comparison of blood products PRF and I-PRF with bone substitute material for bone preservation in lower molar teeth region

Comparative evaluation of the efficacy of PRF and I-PRF with osseous bone graft for socket preservation in the mandibular molar region â?? A randomized clinical trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023432
Enrollment
26
Registered
2020-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R50-R69- General symptoms and signs

Interventions

Intervention1: Socket preservation: Placement of PRF or I-PRF with osseous bone graft in the socket Control Intervention1: Socket preservation: Comparing efficay of PRF and I-PRF for socket preservati

Sponsors

Aldridge Jose Fernandes
Lead Sponsor
Institutional Thesis Grant
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients requiring extraction involving mandibular first and second molar and willing for implant placement. Residual extraction sockets possessing intact bone in all dimensions and an occlusion suitable for planned treatment

Exclusion criteria

Exclusion criteria: Patients with abusive habits such as smoking or aloholism Pregnant or lactating women Patients suffering from systemic diseases Patients with platelet count less than 200,000/cubic mm Patients with persisting periapical infection following antibiotic therapy Patients contraindicated for implant placement or extraction.

Design outcomes

Primary

MeasureTime frame
Bone density Mean ridge width difference between outer border of buccal and lingual cortical plate Socket depth Histological evaluation of bone core sample at baseline and 6 monthsTimepoint: At baseline At 6 months

Secondary

MeasureTime frame
Qualitative assessment of postoperative pain using questionnaireTimepoint: Day 1 to Day 7

Countries

India

Contacts

Public ContactDR Lakshmi P

Manipal College of Dental Sciences, Manipal

get2rupaliagnihotri@gmail.com08202922173

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026