Health Condition 1: H052- Exophthalmic conditions
Conditions
Interventions
Intervention1: Orbital decompression surgery: The patients will undergo Unilateral orbital decompression surgery, with bony wall and fat decompression, depending on severity of proptosis, under genera
Sponsors
Guru Nanak Eye Centre
Eligibility
Inclusion criteria
Inclusion criteria: Only Moderate and severe TED with modified Clinical Activity Score less than 4/10 (inactive TED) Non smokers or smokers who have left smoking for more than 1 year
Exclusion criteria
Exclusion criteria: All known cases of Diabetes Mellitus, Coronary Artery Disease, Optic Neuropathy due to causes other than Dysthyroid Optic Neuropathy, Optic Atrophy, Exposure keratopathy, Pregnancy, Uncontrolled hypertension, Hyperlipidemia, Active smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome will be measured in terms of change in orbital blood flow parameters – namely PSV, EDV & RI in Ophthalmic artery and Central retinal artery, measured by Colour Doppler imaging at end of 3 months.Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome will be measured in terms of complications of surgery in terms of ocular motility, diplopia, proptosis (by Hertels’exophthalmometer), OCT RNFL thickness and sensations along distribution of infraorbital nerve. Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Shalin Shah
Guru Nanak Eye Centre
Outcome results
None listed