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Study of blood clot product following processing of blood in medical grade glass and plastic test tubes

Comparative evaluation of the characteristic of platelet rich fibrin and advanced platelet rich fibrin derived through centrifugation of blood in borosilicate glass or polypropylene plastic centrifugation tubes in an ex-vivo study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023383
Enrollment
20
Registered
2020-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Preparation of PRF in borosilicate glass test tubes: 10 ml of whole blood to be centrifuged in boroslicate glass test tube under centrifugation protocol for PRF. Intervention2: Preparat

Sponsors

Dr Sukalkar Shrushti Mahendra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy participants above the age of 18 years of age rendering informed consent to participate in the study. 2.Normal hemogram with parameters of Hb, WBC,RBC, and platelet counts within normal range. Hb female: 12-15mg/dl Hb male: 13-17mg/dl RBC: 4.1-5.1 million/cu.mm WBC: 4400-11300 cells/mcl Platelet counts: 150,000-450,000 micro liter.

Exclusion criteria

Exclusion criteria: 1.History of hospitalization within past 3-6 months. 2.Participants on antibiotics or any drugs past 6 months 3.Participants taking anticoagulant or anti-platelet drugs. 4.Participants with habit of smoking or alcohol intake. 5.Pregnant and lactating mothers. 6.Participants in active phase of menstruation (day 1-7).

Design outcomes

Primary

MeasureTime frame
1.Difference in platelets and WBC counts between the whole blood and residual serum assessed using an automated cell analyzer following centrifugation of 10 ml of blood in either borosilicate glass or polypropylene plastic centrifugation tubes abiding to PRF and A-PRF centrifugation protocols.Timepoint: One time blood collection at baseline.—

Secondary

MeasureTime frame
The distribution of platelets and WBCs within the head, middle and tail region of the fibrin mesh of platelet rich fibrin (PRF) and advanced platelet rich fibrin (A-PRF) membranes generated through centrifugation of 10 ml blood using either borosilicate glass or polypropylene centrifugation test tubes abiding to PRF and A-PRF centrifugation protocols under light microscopy at 40 x magnification. Timepoint: one time blood collection at baseline.—

Countries

India

Contacts

Public ContactDr Vineet Kini

MGM Dental College and Hospital, Navi Mumbai

drvinkin@gmail.com9769804390

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026