FindTrial
Sign In

Drugs when injected in a particular space of backbone leads to loss of sensation and paralysis of lower region. Drugs used in this study are chloroprocaine (local anesthetic responsible for all these effects) & fentanyl (to increase the efficiency of procedure).

Comparing the efficacy of Spinal chloroprocaine with and without fentanyl in lower abdominal and lower limb day care surgeries: a prospective, double blind randomised controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023353
Enrollment
52
Registered
2020-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K629- Disease of anus and rectum, unspecified Health Condition 2: K64- Hemorrhoids and perianal venous thrombosis Health Condition 3: S80-S89- Injuries to the knee and lower leg

Interventions

Intervention1: Fentanyl as an adjuvant to chloroprocaine: Adding fentanyl to chloroprocaine while giving spinal anesthesia . 1% Chloroprocaine 3 ml and 0.4 ml (20ug) of Fentanyl intrathecally . Contr

Sponsors

Department of Anaesthesia and Intensive Care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists (ASA) grade l &II 2.BMI 20 to 35 kg/m2

Exclusion criteria

Exclusion criteria: 1.Pre-existing local infectious at the site of spinal block. 2.Patients with coagulopathy and bleeding disorders. 3.Contraindications or allergy to Chloroprocaine and Fentanyl. 4. Patients having pain in any other area other than surgery site. 5. Patients having sensory or motor problem in lower limb. Patients having hemodynamic instability. -Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
To compare the onset and duration of motor blockTimepoint: Outcomes will be assessed at baseline, during intraoperative period and up to 6 hours of spinal block.—

Secondary

MeasureTime frame
To compare characteristics of spinal block (onset and duration of analgesia) haemodynamics (heart rate, blood pressure), characteristics of spinal block (onset of block, analgesia) itching, nausea/ vomiting if any as secondary outcomesTimepoint: Secondary outcomes will be assessed along with primary outcomes at baseline, during intraoperative period and up to 6 hours after the spinal block.—

Countries

India

Contacts

Public ContactDrLakesh K Anand

Government Medical College and Hospital Sector 32 Chandigarh

lkanand11@gmail.com9646121522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026