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Effect of Polycystic ovarian syndrome(PCOS) on female egg and its surrounding environment

Impact of polycystic ovary syndrome (PCOS) on epigenetic integrity of granulosa cells and ultrastructure of oocytes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/02/023320
Enrollment
60
Registered
2020-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R888- Abnormal findings in other body fluids and substances

Interventions

None listed

Sponsors

Department of Clinical Embryology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with and without PCOS, age < 35 years were included

Exclusion criteria

Exclusion criteria: Patients with endometriosis, diabetics, hyperthyroidism or age > 35 years were excluded from the study

Design outcomes

Primary

MeasureTime frame
From this study we are expected to uderstand the level of testosterone and luteinizing hormone in follicular fluid, gene expression of de novo methyl transferase in granulosa cells and global methylation, ultrastructure of immature oocyte and fertilization and embryonic developmentTimepoint: 10.09.2019 to 09.09.2020

Secondary

MeasureTime frame
Better understanding of PCOS characteristicsTimepoint: 10.09.2019 to 09.09.2020

Countries

India

Contacts

Public ContactDr Shubashree Uppangala

Kasturba Medical College, Manipal

shubha.u@manipal.edu9480009731

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026