A study looking at the effect of two different pain medications compared to standard treatment in decreasing pain and improving recovery (ability to tolerate orally, early discharge from hospital, comfort, sleep) in patients undergoing anal fistula surgery in day care

Efficacy of a single dose intravenous Lidocaine and Ketamine combination in improving quality of recovery in patients coming for anal fistula surgery in a day care setting - A prospective double blinded randomized control trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/02/023305

Enrollment

100

Registered

2020-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K929- Disease of digestive system, unspecified

Interventions

Intervention1: Ketamine,Lignocaine: combination of inj ketamine 0.2mg/kg and inj lignocaine 2 mg /kg in a 10cc syringe given at the time of induction of anaesthesia Control Intervention1: Placebo: nor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient diagnosed with fistula in ano planned for ambulatory EUA LOF procedure 2. ASA I and II

Exclusion criteria

Exclusion criteria: 1. Age less than 18 years 2. ASA III to IV 3. Ischemic heart disease 3. Difficult airway 4. Valvular heart disease 5. Obesity BMI > 30kg/m2 6. Weight less than 50 kg

Design outcomes

Primary

Measure	Time frame
Post-Operative Pain scoreTimepoint: Post-Operative Pain score	—

Secondary

Measure	Time frame
1.Post-operative recovery score 2.Hemodynamic stability, 3.Intraoperative laryngospasm during anal dilatation 4.Total Intraoperative and postoperative requirements of opioids 5.Time to Drink,Eat and Mobilise (DREAM) 6.Time to meet discharge criteria. Timepoint: End of surgery	—

Countries

India

Contacts

Public ContactDr Sarina Mary George

Christian Medical College vellore

tonythomson@cmcvellore.ac.in9500242412

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026