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Correlation of MRI guided pre-operative hippocampal volume with the duration of emergence from general anesthesia in elective neurosurgical patients undergoing cranial surgeries: An observational study

Correlation of pre-operative hippocampal volume measured with MRI and duration of emergence from general anesthesia in elective neurosurgical patients undergoing cranial surgeries: An observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/02/023292
Enrollment
100
Registered
2020-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

NIMHANS HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients above the age of 18 years who are scheduled for elective cranial surgeries under general anaesthesia 2. Patients having preoperative MRI Brain [T1-MPRAGE sequence] 3. GCS of 15

Exclusion criteria

Exclusion criteria: 1.Patients with a. Hypothyroidism b. GCS c. Emergence time beyond 1 hour after discontinuing anesthesia [8] 2.Patients having excision of hippocampus and amygdala 3. Patients with temporal lobe pathology

Design outcomes

Secondary

MeasureTime frame
To evaluate if there exists a gender difference in patterns of emergenceTimepoint: 1 hour during recovery;To evaluate the relationship between preoperative hippocampus volume and functional reserve of the patient with the time and pattern of emergence after general anesthesiaTimepoint: 1 hour during recovery

Primary

MeasureTime frame
To evaluate the correlation between preoperative hippocampus volume and duration of emergence after general anesthesiaTimepoint: 1 hour after the end of anaesthesia

Countries

India

Contacts

Public ContactPRAMOD KALGUDI

NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES

n_bhadri@yahoo.com9535351200

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026