Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: patients recieving Genicular Nerve Radiofrequency Ablation with Duloxetine 60 mg HS: Patients will be receiving duloxetine 60 mg HS with genicular nerve block
Control Intervention1: pat
Sponsors
AIIMS Jodhpur Research Committee
Eligibility
Inclusion criteria
Inclusion criteria: Patients with diagnosis of radiologically verified grade III or IV osteoarthritis according to the Kellgren-Lawrence Grading Scale who are not willing or not fit for knee replacement due to concomitant comorbid medical diseases
Exclusion criteria
Exclusion criteria: Multiple joint involvement, History of knee surgery Experiencing acute knee pain with inflammation findings Connective tissue disease affecting the knee joint Serious psychiatric disorder or neurological disease Sciatica Current use of anticoagulant drugs Having received intra-articular steroid or hyaluronic acid injection within the previous 3 months. Patient not willing to participate in study Allergy to duloxetine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison in improvement of quality of Life by WOMAC score in both groups.Timepoint: 2 weeks, 1 month, 2 months and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparison of NRS score in both group 2. Total analgesic consumption in both groups 3. Patient satisfaction in both groups 4. To note the associated complications/ side effects of study drug- abnormal proprioception, numbness, paraesthesia, neuralgia, and motor weakness, nausea, constipation and loss of appetite. Timepoint: 2 weeks, 1 month, 2 months and 3 months | — |
Countries
India
Contacts
Public ContactSOMYA GOEL
AIIMS Jodhpur
Outcome results
None listed