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to achieve maximum anaesthetic success using ketorolac and pregabalin premedication with 1.7mL of articaine using Inferioor alveolar block with infiltration in symptomatic teeth

Comparative Evaluation of Anaesthetic Success after Ketorolac and Pregabalin Oral Premedication for Inferior Alveolar Nerve Block with Buccal Infiltration in Symptomatic Mandibular Molars with Irreversible Pulpitis-- A Prospective, Randomized, Controlled, Double-Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/02/023261
Enrollment
150
Registered
2020-02-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: articaine is used: The dentist administering the local anesthetic agent.The access opening and instrumentation will be assigned to different dentist. Control Intervention1: nil: nil

Sponsors

dr suruchi agrawal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Symptomatic irreversible pulpitis 2 Patients with active pain in a mandibular first or/and second molar, 3 Patients in good health, with no previous history of allergy to any kind of local anesthesia, sulphites or other drugs that would alter pain perception. 4 Prolonged response to cold testing with Endo-frost (Roeko Langenace, Germany) 5 Absence of any periapical radiolucency on periapical radiographs 6 A vital coronal pulp on access opening.

Exclusion criteria

Exclusion criteria: 1 Subjects younger than 18 years and older than 60 2 History of significant medical problems 3 Taken central nervous system depressants or any analgesic medication within 8 hours 4 Pregnancy 5 Allergy to articaine, ketorolac, pregabalin 6 Unable to give informed consent.

Design outcomes

Primary

MeasureTime frame
compare the effect of oral premedication with ketorolac and pregabalin on anesthetic efficacy of inferior alveolar nerve block and buccal infiltration in symptomatic patients with irreversible pulpitisTimepoint: pain assessment done at 15 minutes

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Suruchi Agrawal

SGT Dental College

drmandeepsgrewal@yahoo.co.in9810805880

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026